Diffuse optical measurement of hemoglobin and cerebral blood flow in rat brain during hypercapnia, hypoxia and cardiac arrest.

@article{Culver2003DiffuseOM,
  title={Diffuse optical measurement of hemoglobin and cerebral blood flow in rat brain during hypercapnia, hypoxia and cardiac arrest.},
  author={Joseph P. Culver and Turgut Durduran and Cecil C C Cheung and Daisuke Furuya and Joel H. Greenberg and A. G. Yodh},
  journal={Advances in experimental medicine and biology},
  year={2003},
  volume={510},
  pages={293-7}
}
We have demonstrated the ability to concurrently measure relative changes in cerebral blood flow, hemoglobin concentration, and hemoglobin oxygenation with a single non-contact, non-invasive instrument. Our measurements from rat hypercapnia, hypoxia and cardiac arrest models are in reasonable agreement with the literature, and offer the possibility for further growth and quantification. The optical techniques used in this study are attractive also because they enable experimenters to measure… CONTINUE READING

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