Diffuse mode of tumor cell invasion and expression of mutant p53 protein but not of p21 protein are correlated with treatment failure in oral carcinomas and their metastatic foci.

@article{Osaki2000DiffuseMO,
  title={Diffuse mode of tumor cell invasion and expression of mutant p53 protein but not of p21 protein are correlated with treatment failure in oral carcinomas and their metastatic foci.},
  author={Tokio Osaki and Tomo Kimura and Yukihiro Tatemoto and Li Dapeng and Kazunori Yoneda and Toshiya Yamamoto},
  journal={Oncology},
  year={2000},
  volume={59 1},
  pages={
          36-43
        }
}
Lack of control of metastatic foci is the most prevalent cause of death in patients with oral carcinomas, and it is important for tumor control to identify the factors that predispose patients to death. In the present study, we examined 225 patients with oral squamous cell carcinoma and investigated the immunohistopathological characteristics of 43 tumors that led to death, comparing them with those of the non-lethal tumors. In the 43 patients, lack of control of the primary site, lymph node… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 64 REFERENCES

Assessment of the biological malignancy of hepatocellular carcinoma: relationship to clinicopathological factors and prognosis.

  • Clinical cancer research : an official journal of the American Association for Cancer Research
  • 1998