Diffuse large B-cell lymphoma: current treatment approaches.

  title={Diffuse large B-cell lymphoma: current treatment approaches.},
  author={Loretta J Nastoupil and Adam Anna Vari Kate Rawles Wesley Cragg Steven Rose and Christopher R Flowers},
  volume={26 5},
Diffuse large B-cell lymphoma (DLBCL) is the most commonly occurring lymphoid malignancy. While a series of trials support R-CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone, plus rituximab)-21 as the standard of care for all patients, DLBCL has substantial biological and clinical heterogeneity, leading to marked differences in outcomes for disease subgroups. We examine clinical, biological, and functional imaging techniques for risk-stratifying patients, and we review… CONTINUE READING


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