We observed three cases of knots after peripheral nerve catheterism. Catheter removal was impossible and required the intervention of an anaesthetist. This complication should be known and included in the training of nurses. The analgesic technique by peripheral nerve catheter is currently used for the treatment of acute postoperative pain and starts to be used for the treatment of chronic pain. The catheter removal should be included in a protocol. One solution might be the use of a network to meet all the complications that happen in continuous peripheral nerve blocks, particularly at home.