Difficulties in assessing brain death in a case of benzodiazepine poisoning with persistent cerebral blood flow

@article{Marrache2004DifficultiesIA,
  title={Difficulties in assessing brain death in a case of benzodiazepine poisoning with persistent cerebral blood flow},
  author={Fr{\'e}d{\'e}ric Marrache and Bruno M{\'e}garbane and S Pirnay and Abdel Rhaoui and Marie Thuong},
  journal={Human and Experimental Toxicology},
  year={2004},
  volume={23},
  pages={503 - 505}
}
  • Frédéric Marrache, Bruno Mégarbane, +2 authors Marie Thuong
  • Published 2004
  • Medicine
  • Human and Experimental Toxicology
  • Assessing brain death may sometimes be difficult, with isoelectric EEG following psychotrope overdoses or normal cerebral blood flow (CBF) persisting despite brain death in the case of ventricular drainage or craniotomy. A 42-year-old man, resuscitated after cardiac arrest following a suicidal ingestion of ethanol, bromazepam and zopiclone, was admitted in deep coma. On day 4, his brainstem reflexes and EEG activity disappeared. On day 5, his serum bromazepam concentration was 817 ng/ml… CONTINUE READING

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