Difficult-to-Treat Gouty Arthritis

@article{Schlesinger2011DifficulttoTreatGA,
  title={Difficult-to-Treat Gouty Arthritis},
  author={Dr Naomi Schlesinger},
  journal={Drugs},
  year={2011},
  volume={71},
  pages={1413-1439}
}
Gouty arthritis is the most common inflammatory arthritis in adults and is characterized by very painful flares. Gouty arthritis results from an elevated body uric acid pool, which leads to deposition of monosodium urate crystals, mainly in the joints. These crystals trigger the release of proinflammatory cytokines, in particular interleukin (IL)-1β, which stimulates inflammation. Gouty arthritis can progress to a chronic, deforming and physically disabling disease through the development of… CONTINUE READING

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