Differing patterns of striatal 18F-dopa uptake in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy.

@article{Brooks1990DifferingPO,
  title={Differing patterns of striatal 18F-dopa uptake in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy.},
  author={David J. Brooks and Vicente Ib{\'a}{\~n}ez and Guy V Sawle and Niall Quinn and A. J. Lees and Christopher J. Mathias and R B Bannister and C. David Marsden and Richard S. Frackowiak},
  journal={Annals of neurology},
  year={1990},
  volume={28 4},
  pages={547-55}
}
Using positron emission tomography (PET), we studied regional striatal 18F-dopa uptake in 16 patients with L-dopa-responsive Parkinson's disease (PD), 18 patients with multiple system atrophy, and 10 patients with progressive supranuclear palsy. Results were compared with those of 30 age-matched normal volunteers. The patients with PD showed significantly reduced mean uptake of 18F-dopa in the caudate and putamen compared to controls, but while function in the posterior part of the putamen was… CONTINUE READING
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