Differing Evolutionary Histories of the ACTN3*R577X Polymorphism among the Major Human Geographic Groups

Abstract

It has been proposed that the functional ACTN3*R577X polymorphism might have evolved due to selection in Eurasian human populations. To test this possibility we surveyed all available population-based data for this polymorphism and performed a comprehensive evolutionary analysis of its genetic diversity, in order to assess the action of adaptive and random… (More)
DOI: 10.1371/journal.pone.0115449

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