Differentiation of rat hippocampal neurons induced by estrogen in vitro: effects on neuritogenesis and Na, K-ATPase activity.

@article{Blanco1990DifferentiationOR,
  title={Differentiation of rat hippocampal neurons induced by estrogen in vitro: effects on neuritogenesis and Na, K-ATPase activity.},
  author={Gloria Blanco and Hugo D. D{\'i}az and Hugo F. Carrer and Luis A Beaug{\'e}},
  journal={Journal of neuroscience research},
  year={1990},
  volume={27 1},
  pages={47-54}
}
To gain insight into the mechanisms responsible for differentiation of hippocampal neurons growing in vitro, the effects of estrogen on neuritic development and on activity and distribution of isoforms of the Na, K-ATPase, were evaluated. Dissociated cells from hippocampi of 19-day-old rat fetuses were raised for 5 days in the presence or absence of 100 nM estradiol-17 beta (E2) in minimum essential medium supplemented either with 10% untreated fetal calf serum (MEM-10) or with 10% fetal calf… CONTINUE READING

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