Differentiation of pancreatic ductal carcinoma cells associated with selective expression of protein kinase C isoforms

Abstract

Background: The signal transduction pathways important in regulating the growth and differentiation of malignant cells are poorly understood. Recent evidence has implicated activation of the protein kinase C (PKC) family of signaling proteins in pancreatic carcinoma during cytokine-induced cytostasis and differentiation. Methods: A human pancreatic… (More)
DOI: 10.1007/BF02306090

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