Differentiation of neuromuscular junctions in cultures of embryonic Drosophila cells.

@article{Seecof1972DifferentiationON,
  title={Differentiation of neuromuscular junctions in cultures of embryonic Drosophila cells.},
  author={Robert L. Seecof and Raymond L. Teplitz and Ines Gerson and Kazuo Ikeda and J. James Donady},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1972},
  volume={69 3},
  pages={566-70}
}
Cultures were prepared of embryonic cells from Drosophila melanogaster. Neurons and myocytes differentiated in vitro from their respective stem cells. Electron microscopy showed that neuromuscular junctions formed where axons contacted myocytes. Electrical stimuli were applied to axons and these caused contractions of innervated myocytes. This is the first report of insect or other invertebrate neuromuscular junctions differentiating in vitro. In addition, this is the first system reported in… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

Similar Papers

Loading similar papers…