Differentiation of human skeletal muscle cells in culture: maturation as indicated by titin and desmin striation

@article{Ven1992DifferentiationOH,
  title={Differentiation of human skeletal muscle cells in culture: maturation as indicated by titin and desmin striation},
  author={Peter F. M. van der Ven and Gert Schaart and Paul H. K. Jap and Rob C. A. Sengers and Ad M. Stadhouders and Francs C. S. Ramaekers},
  journal={Cell and Tissue Research},
  year={1992},
  volume={270},
  pages={189-198}
}
This report describes a phenotyping study of differentiating human skeletal muscle cells in tissue culture. Satellite cells (adult myoblasts), isolated from biopsy material, showed a proliferative behaviour in high-nutrition medium, but fused to form myotubes when grown in low-nutrition medium. The expression and structural organization of the intermediate filament proteins desmin and vimentin as well as the sarcomeric constituents α-actin, α-actinin, nebulin, myosin and especially titin during… CONTINUE READING

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Mentioned Connections BETA
ActinsNo subtypeconnectin
Four to 10 days after the medium change , mature myotubes showed desmin , titin , α-actinin , nebulin , sarcomeric myosin and actin cross - striations , while vimentin was no longer detected .
connectinNo subtypeActins
Four to 10 days after the medium change , mature myotubes showed desmin , titin , α-actinin , nebulin , sarcomeric myosin and actin cross - striations , while vimentin was no longer detected .
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