Differentiation of human embryonic stem cells toward the chondrogenic lineage.

  title={Differentiation of human embryonic stem cells toward the chondrogenic lineage.},
  author={Wei Seong Toh and Zheng Yang and Boon Chin Heng and Tong Cao},
  journal={Methods in molecular biology},
Human embryonic stem cells (hESCs) have the ability to self-replicate and differentiate into cells from all three embryonic germ layers, thereby holding great promise for tissue regeneration applications. However, controlling the differentiation of hESCs and obtaining homogenous differentiated cell populations still remain a challenge. We present a highly efficient and reproducible experimental system that mimics the three-dimensional (3-D) environment of in vivo chondrogenesis and that… CONTINUE READING
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