Differentiation of glioblastoma multiforme from metastatic brain tumor using proton magnetic resonance spectroscopy, diffusion and perfusion metrics at 3 T

@article{Tsougos2012DifferentiationOG,
  title={Differentiation of glioblastoma multiforme from metastatic brain tumor using proton magnetic resonance spectroscopy, diffusion and perfusion metrics at 3 T},
  author={Ioannis Tsougos and Patricia Svolos and Evanthia Kousi and Konstantinos N Fountas and Kyriaki Theodorou and Ioannis Fezoulidis and Eftychia Z. Kapsalaki},
  journal={Cancer Imaging},
  year={2012},
  volume={12},
  pages={423 - 436}
}
Abstract Purpose: To assess the contribution of 1H-magnetic resonance spectroscopy (1H-MRS), diffusion-weighted imaging (DWI), diffusion tensor imaging (DTI) and dynamic susceptibility contrast-enhanced (DSCE) imaging metrics in the differentiation of glioblastomas from solitary metastasis, and particularly to clarify the controversial reports regarding the hypothesis that there should be a significant differentiation between the intratumoral and peritumoral areas. Methods: Conventional MR… Expand
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References

SHOWING 1-10 OF 61 REFERENCES
Diffusion-tensor MR imaging of intracranial neoplasia and associated peritumoral edema: introduction of the tumor infiltration index.
TLDR
Peritumoral diffusion-tensor MR imaging metrics enable the differentiation of solitary intraaxial metastatic brain tumors from gliomas and enables one to distinguish presumed tumor-infiltrated edema from purely vasogenic edema. Expand
Diagnostic examination performance by using microvascular leakage, cerebral blood volume, and blood flow derived from 3-T dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging in the differentiation of glioblastoma multiforme and brain metastasis
IntroductionConventional magnetic resonance (MR) imaging has limited capacity to differentiate between glioblastoma multiforme (GBM) and metastasis. The purposes of this study were: (1) to compareExpand
Combination of single-voxel proton MR spectroscopy and apparent diffusion coefficient calculation in the evaluation of common brain tumors.
TLDR
Combination of calculated ADC values from tumoral core and specific relative metabolite ratios acquired by MR spectroscopy added more information to MR imaging in the differentiation and grading of brain tumors and were more useful together than each alone. Expand
In vivo single-voxel proton MR spectroscopy in the differentiation of high-grade gliomas and solitary metastases.
TLDR
1HMRS is a useful method in the distinction of high-grade gliomas and metastases and may also may provide useful prognostic information. Expand
Differentiation between glioblastomas and solitary brain metastases using diffusion tensor imaging
TLDR
It is concluded that DTI metrics, used individually or combined, have a potential as a non-invasive measure to differentiate glioblastomas from metastases. Expand
Proton magnetic resonance spectroscopy in the distinction of high-grade cerebral gliomas from single metastatic brain tumors
TLDR
The results of this study demonstrate that MRS can differentiate high-grade gliomas from metastases, especially with peritumoral measurements, supporting the hypothesis that M RS can detect infiltration of tumor cells in the perituoral edema. Expand
Peritumoral brain regions in gliomas and meningiomas: investigation with isotropic diffusion-weighted MR imaging and diffusion-tensor MR imaging.
TLDR
A role for diffusion MR imaging in the detection of tumoral infiltration that is not visible on conventional MR images is indicated, and changes in ADC and FA decreases in peritumoral hyperintense regions between these tumors approached but did not reach significance. Expand
Distinction between high-grade gliomas and solitary metastases using peritumoral 3-T magnetic resonance spectroscopy, diffusion, and perfusion imagings
TLDR
Although conventional MR imaging characteristics of solitary metastases and primary high-grade gliomas may sometimes be similar, the peritumoral perfusion-weighted and spectroscopic MR imaging enable distinction between the two. Expand
The role of diffusion-weighted imaging in patients with brain tumors.
TLDR
The ADC may predict the degree of malignancy of astrocytic tumors, although there is some overlap between ADCs of grade IIAstrocytomas and glioblastomas. Expand
High-grade gliomas and solitary metastases: differentiation by using perfusion and proton spectroscopic MR imaging.
TLDR
Although conventional MR imaging characteristics of solitary metastases and primary high-grade gliomas may sometimes be similar, perfusion-weighted and spectroscopic MR imaging enable distinction between the two. Expand
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