Differentiation and telomerase activity of human mesenchymal stem cells.

  title={Differentiation and telomerase activity of human mesenchymal stem cells.},
  author={Wen-Yu Fu and Yan-meng Lu and Ying-jie Piao},
  journal={Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA},
  volume={21 11},
OBJECTIVE: To study the differentiation of human mesenchymal stem cells (MSCs) derived from human fetal bone marrow and observe its telomerase activity. METHODS: MSCs were isolated from fetal bone marrow of the femur followed by cell culture and amplification. In situ hybridization was employed to detect telomerase activity in the MSCs. Subcutaneous implantation of MSCs into nude mice was performed to observe their differentiation potentials 4 weeks after the implantation. RESULTS: Human MSCs… CONTINUE READING

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