Differentiation and quantification of inflammation, demyelination and axon injury or loss in multiple sclerosis.

@article{Wang2015DifferentiationAQ,
  title={Differentiation and quantification of inflammation, demyelination and axon injury or loss in multiple sclerosis.},
  author={Yong Wang and Peng Sun and Qing Wang and Kathryn Trinkaus and Robert E. Schmidt and Robert T. Naismith and Anne H. Cross and S K Song},
  journal={Brain : a journal of neurology},
  year={2015},
  volume={138 Pt 5},
  pages={1223-38}
}
Axon injury/loss, demyelination and inflammation are the primary pathologies in multiple sclerosis lesions. Despite the prevailing notion that axon/neuron loss is the substrate of clinical progression of multiple sclerosis, the roles that these individual pathological processes play in multiple sclerosis progression remain to be defined. An imaging modality capable to effectively detect, differentiate and individually quantify axon injury/loss, demyelination and inflammation, would not only… CONTINUE READING
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