Differentiation and immune function of human dendritic cells following infection by respiratory syncytial virus.

@article{Jones2006DifferentiationAI,
  title={Differentiation and immune function of human dendritic cells following infection by respiratory syncytial virus.},
  author={Allison Jones and Ian K. M. Morton and Lynsey Hobson and Gareth J S Evans and Mark L Everard},
  journal={Clinical and experimental immunology},
  year={2006},
  volume={143 3},
  pages={513-22}
}
RSV causes annual epidemics of bronchiolitis in winter months resulting in the hospitalization of many infants and the elderly. Dendritic cells (DCs) play a pivotal role in coordinating immune responses to infection and some viruses skew, or subvert, the immune functions of DCs. RSV infection of DCs could alter their function and this could explain why protection after natural RSV infection is incomplete and of short duration. In this study, this interaction between DCs and RSV was investigated… CONTINUE READING

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