Differentiation and Gene Flow among European Populations of Leishmania infantum MON-1

  title={Differentiation and Gene Flow among European Populations of Leishmania infantum MON-1},
  author={Katrin Kuhls and C. Chicharro and Carmen Ca{\~n}avate and Sofia Cortes and L{\'e}nea Maria da Graça Campino and Christos Haralambous and Ketty P. Soteriadou and Francine Pratlong and J A Dedet and Isabel L. Mauricio and Michael Alexander Miles and M. W. G. von der Schaar and Sebastian Ochsenreither and Oliver A. Radtke and Gabriele Sch{\"o}nian},
  journal={PLoS Neglected Tropical Diseases},
  pages={188 - 189}
BACKGROUND Leishmania infantum is the causative agent of visceral and cutaneous leishmaniasis in the Mediterranean region, South America, and China. MON-1 L. infantum is the predominating zymodeme in all endemic regions, both in humans and dogs, the reservoir host. In order to answer important epidemiological questions it is essential to discriminate strains of MON-1. METHODOLOGY/PRINCIPAL FINDINGS We have used a set of 14 microsatellite markers to analyse 141 strains of L. infantum mainly… CONTINUE READING


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