• Corpus ID: 51998758

Differentiating the Therapeutic uses of EPA and DHA in clinical practice October 2008

  title={Differentiating the Therapeutic uses of EPA and DHA in clinical practice October 2008},
  • Published 2012
  • Medicine



Fatty acid modulation of endothelial activation.

Consumption of the n-3 fatty acid docosahexaenoic acid (DHA) reduced endothelial expression of vascular cell adhesion molecule 1 (VCAM-1) and reduced the adhesion of human monocytes and monocytic U937 cells to cytokine-stimulated endothelial cells, indicating a pretranslational effect.

Effects of highly purified eicosapentaenoic acid and docosahexaenoic acid on hemodynamics in humans.

It is concluded that dietary DHA and EPA influence heart rate and that the fatty acid composition of plasma phospholipids may affect cardiac mechanics in humans.

The independent effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular risk factors in humans

Controlled studies in humans now demonstrate that docosahexaenoic acid, although often present in lower quantities, has equally important anti-arrhythmic, anti-thrombotic and anti-atherogenic effects.

The effect of supplementation with fish oil during pregnancy on breast milk immunoglobulin A, soluble CD14, cytokine levels and fatty acid composition

Background Breast milk contains many immunomodulatory factors (soluble CD14 (sCD14), IgA and cytokines) with the potential to influence infant immune development.

Serum fatty acids and the risk of coronary heart disease.

Findings are consistent with other evidence indicating that saturated fatty acids are directly correlated with CHD and that omega-3 polyunsaturated fatty acidsAreas of associations were present after adjustment for blood lipid levels, other mechanisms, such as a direct effect on blood clotting, may be involved.

Blood levels of long-chain n-3 fatty acids and the risk of sudden death.

The n-3 fatty acids found in fish are strongly associated with a reduced risk of sudden death among men without evidence of prior cardiovascular disease.

Three-Year Outcomes of Dietary Fatty Acid Modification and House Dust Mite Reduction in the Childhood Asthma Prevention Study

To measure the effects of dietary supplementation with ω-3 fatty acids and house d-e (HDM) allergen avoidance in children with a family history of asthma, children at high risk for asthma were enrolled antenatally.

The Use of Fish Oil Supplements in Clinical Practice: A Review

This review will focus on the data concerning fish consumption, fish oil supplements and their fatty acids as it pertains to clinical outcomes, with an emphasis on cardiovascular health.