Differentiating Sarcopenia and Cachexia Among Patients With Cancer

@article{Peterson2017DifferentiatingSA,
  title={Differentiating Sarcopenia and Cachexia Among Patients With Cancer},
  author={Sarah J. Peterson and Marisa Mozer},
  journal={Nutrition in Clinical Practice},
  year={2017},
  volume={32},
  pages={30–39}
}
Patients with cancer are at an increased risk for muscle loss via 2 distinct mechanisms: sarcopenia, defined as the age-associated decrease in muscle mass related to changes in muscle synthesis signaling pathways, and/or cachexia, defined as cytokine-mediated degradation of muscle and adipose depots. Both wasting disorders are prevalent; among patients with cancer, 15%–50% are sarcopenic and 25%–80% are cachectic. Muscle mass may be difficult to quantify in overweight/obese individuals. Often… 

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