Differentially methylated genes and androgen receptor re-expression in small cell prostate carcinomas.

@article{Kleb2016DifferentiallyMG,
  title={Differentially methylated genes and androgen receptor re-expression in small cell prostate carcinomas.},
  author={Brittany Kleb and Marcos R. H. Est{\'e}cio and Jiexin Zhang and Vassiliki Tzelepi and Woonbok Chung and Jaroslav Jelinek and Nora M. Navone and Salahaldin A. Tahir and Victor E. Marquez and Jean-Pierre Issa and Sankar N. Maity and Ana Aparicio},
  journal={Epigenetics},
  year={2016},
  volume={11 3},
  pages={184-93}
}
Small cell prostate carcinoma (SCPC) morphology is rare at initial diagnosis but often emerges during prostate cancer progression and portends a dismal prognosis. It does not express androgen receptor (AR) or respond to hormonal therapies. Clinically applicable markers for its early detection and treatment with effective chemotherapy are needed. Our studies… CONTINUE READING