Differentially expressed proteins of MCF-7 human breast cancer cells affected by Zilongjin, a complementary Chinese herbal medicine.

@article{Tian2010DifferentiallyEP,
  title={Differentially expressed proteins of MCF-7 human breast cancer cells affected by Zilongjin, a complementary Chinese herbal medicine.},
  author={Zhi-hua Tian and Zheng-Fu Li and Shao-bo Zhou and Yun-yan Liang and Da-cheng He and Dai-shu Wang},
  journal={Proteomics. Clinical applications},
  year={2010},
  volume={4 5},
  pages={550-9}
}
PURPOSE Zilongjin, a complementary Chinese herbal medicine, has been used to alleviate the adverse effects of chemotherapeutic drugs in cancer therapy. However, the mechanisms of anti-cancer activity of Zilongjin are still largely unkonwn. EXPERIMENTAL DESIGN First, the proteomic approach of combined 2-DE and ESI-MS/MS was used to investigate the effect of Zilongjin on the protein expression in MCF-7 cells. Then, the differential expression of some proteins was confirmed by Western blot… CONTINUE READING

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