Differentially expressed late constituents of the epidermal cornified envelope.

@article{Marshall2001DifferentiallyEL,
  title={Differentially expressed late constituents of the epidermal cornified envelope.},
  author={Damian Marshall and Matthew J. Hardman and Kerry Nield and Carolyn R. Byrne},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2001},
  volume={98 23},
  pages={13031-6}
}
Barrier activity of skin and internal barrier-forming epithelial linings are conferred by a lipid-corneocyte structure (stratum corneum in skin). The integrity of the corneocytes depends on the outer cornified envelope and is essential for maintenance of barrier function. During epidermal development and differentiation, proteins are sequentially… CONTINUE READING