Differentially expressed genes in zona reticularis cells of the human adrenal cortex.

@article{Wang2001DifferentiallyEG,
  title={Differentially expressed genes in zona reticularis cells of the human adrenal cortex.},
  author={Wei Wang and Luping Yang and Tetsuya Suwa and Peter R Casson and Peter Hornsby},
  journal={Molecular and cellular endocrinology},
  year={2001},
  volume={173 1-2},
  pages={127-34}
}
The zona reticularis (ZR) cell in the human adrenal cortex is responsible for the secretion of dehydroepiandrosterone, but its biology, origin, and putative decrease in number during aging are poorly understood. In the present experiments, we investigated to what extent ZR and zona fasciculata (ZF) cells differ in patterns of gene expression. Both cell types were purified by microdissection from adult adrenal cortex specimens. After a brief period in culture, RNA was harvested from the cells… CONTINUE READING
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