Differential vasodilator effect of nitroglycerin on systemic capacitance and resistance vessels in anesthetized dogs, and the mechanism of its action--a study by measuring mean circulatory pressure and total peripheral resistance.

@article{Nagata1989DifferentialVE,
  title={Differential vasodilator effect of nitroglycerin on systemic capacitance and resistance vessels in anesthetized dogs, and the mechanism of its action--a study by measuring mean circulatory pressure and total peripheral resistance.},
  author={K. Nagata and H. Ito and S. Minatoguchi and I. Hirose and T. Sahashi and H. Wada and K. Takai and I. Watanabe and S. Hirakawa},
  journal={Japanese circulation journal},
  year={1989},
  volume={53 11},
  pages={
          1371-81
        }
}
  • K. Nagata, H. Ito, +6 authors S. Hirakawa
  • Published 1989
  • Medicine
  • Japanese circulation journal
    • The aim of our studies was to examine if the baroreceptor reflex induced by intravenous injection of nitroglycerin (NG) nearly nullifies the vasodilator action of NG on the systemic capacitance vessels in dogs anesthetized with pentobarbital. We performed total spinal anesthesia (TSA) in open-chest dogs to eliminate the baroreceptor reflex. Dogs in which mean blood pressure (MBP) was maintained at about 100 mmHg by continuous intravenous infusion of epinephrine formed the TSA 100 group, and… CONTINUE READING
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