Differential uptake of nanoparticles and microparticles by pulmonary APC subsets induces discrete immunological imprints.

@article{Hardy2013DifferentialUO,
  title={Differential uptake of nanoparticles and microparticles by pulmonary APC subsets induces discrete immunological imprints.},
  author={Charles Linton Hardy and Jeanne S Lemasurier and Rohimah Mohamud and Jun Yao and Sue Dong Xiang and Jennifer M Rolland and R. obyn E. O'Hehir and Magdalena Plebanski},
  journal={Journal of immunology},
  year={2013},
  volume={191 10},
  pages={5278-90}
}
There is increasing interest in the use of engineered particles for biomedical applications, although questions exist about their proinflammatory properties and potential adverse health effects. Lung macrophages and dendritic cells (DC) are key regulators of pulmonary immunity, but little is known about their uptake of different sized particles or the nature of the induced immunological imprint. We investigated comparatively the immunological imprints of inert nontoxic polystyrene nanoparticles… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 57 references

Similar Papers

Loading similar papers…