Differential upregulation of aquaporin-4 mRNA expression in reactive astrocytes after brain injury: potential role in brain edema.

Abstract

Astrocytes and aquaporin-4 (AQP4) play a significant role in brain ion homeostasis. Consequently the regulation of AQP4 mRNA in the CNS after different neurological insults was of interest. A single intrastriatal injection of ringer or quinolinic acid strongly induced AQP4 mRNA in the striatum, specially at the core of the lesion. Colocalization studies… (More)

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Cite this paper

@article{Vizuete1999DifferentialUO, title={Differential upregulation of aquaporin-4 mRNA expression in reactive astrocytes after brain injury: potential role in brain edema.}, author={Mar{\'i}a Vizuete and Jennifer Venero and C. Vargas and Anunciaci{\'o}n Ana Ilundain and Mª Echevarr{\'i}a and A. Machado and J. Cano}, journal={Neurobiology of disease}, year={1999}, volume={6 4}, pages={245-58} }