Differential transcriptomic analysis of spontaneous lung tumors in B6C3F1 mice: comparison to human non-small cell lung cancer.

@article{Pandiri2012DifferentialTA,
  title={Differential transcriptomic analysis of spontaneous lung tumors in B6C3F1 mice: comparison to human non-small cell lung cancer.},
  author={Arun Kumar R Pandiri and Robert C. Sills and V Ziglioli and Thai-vu T Ton and H. L. Hong and Stephanie A. Lahousse and Kevin E. Gerrish and Scott S. Auerbach and Keith R. Shockley and Pierre R. Bushel and Shyamal D. Peddada and Mark J. Hoenerhoff},
  journal={Toxicologic pathology},
  year={2012},
  volume={40 8},
  pages={1141-59}
}
Lung cancer is the leading cause of cancer-related death in people and is mainly due to environmental factors such as smoking and radon. The National Toxicology Program (NTP) tests various chemicals and mixtures for their carcinogenic hazard potential. In the NTP chronic bioassay using B6C3F1 mice, the incidence of lung tumors in treated and control animals… CONTINUE READING