Differential transcriptional response profiles in human myeloid cell populations.

@article{Healy2018DifferentialTR,
  title={Differential transcriptional response profiles in human myeloid cell populations.},
  author={Luke M Healy and Gabrielle Perron and So-Yoon Won and Vijayaraghava T S Rao and M Guiot and Craig S Moore and Amit Bar-Or and Jack P. Antel},
  journal={Clinical immunology},
  year={2018},
  volume={189},
  pages={63-74}
}
This study examines the transcriptional profiles of human adult brain-derived microglia in response to in vitro activating conditions previously used to polarize systemic myeloid cells into M1 and M2 phenotypes. A comparative study is done with monocyte-derived macrophages (MDMs), a myeloid cell type that also participates in disease relevant tissue injury… CONTINUE READING