Differential tissue-regulation of myostatin genes in the teleost fish <ce:italic>Lates calcarifer</ce:italic> in response to fasting. Evidence for functional differentiation

@article{Santis2011DifferentialTO,
  title={Differential tissue-regulation of myostatin genes in the teleost fish <ce:italic>Lates calcarifer</ce:italic> in response to fasting. Evidence for functional differentiation},
  author={Carmelinda De Santis and Dean Robert Jerry},
  journal={Molecular and Cellular Endocrinology},
  year={2011},
  volume={335},
  pages={158-165}
}
Gene or genome duplication is a fundamental evolutionary mechanism leading towards the origin of new genes, or gene functions. Myostatin (MSTN) is a negative regulator of muscle growth that in teleost fish, as a result of genome duplication, is present in double copy. This study provides evidence of differentiation of MSTN paralogs in fish by comparatively exploring their tissue-regulation in the Asian sea bass (Lates calcarifer) when subjected to fasting stress. Results showed differential… CONTINUE READING

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