Differential susceptibility of retinal ganglion cells to reactive oxygen species.

@article{Kortuem2000DifferentialSO,
  title={Differential susceptibility of retinal ganglion cells to reactive oxygen species.},
  author={K R Kortuem and Leann Geiger and Leonard A Levin},
  journal={Investigative ophthalmology & visual science},
  year={2000},
  volume={41 10},
  pages={3176-82}
}
PURPOSE Retinal light exposure is a source of oxidative stress, and retinal cells contain molecules that scavenge or inactivate reactive oxygen species (ROS). Yet, ROS also play a role in signal transduction, and some retinal cells (e.g., neurotrophin-dependent retinal ganglion cells, RGCs) may use ROS as part of the signaling process for cell death. RGCs might therefore have specialized mechanisms for regulating ROS levels. The hypothesis that RGCs might regulate ROS differently from other… CONTINUE READING

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References

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Showing 1-10 of 33 references

Activation of the neutrophil respiratory burst oxidase

RA Clark
J Infect Dis. 1999;179(suppl 2):S309–S317 • 1999

BDNF injected into the superior colliculus reduces developmental retinal ganglion cell death.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1998
View 1 Excerpt

Dose dependent mechanisms of lipid hydroperoxide induce retinal pathology

D Armstrong, T Ueda
Pathophysiology of Lipid Peroxides and Related Species • 1998
View 2 Excerpts

Environmental light and age-related changes in retinal proteins

DT Organisciak, RM Darrow, RA Darrow, LA. Lininger
Photostasis and Related Phenomena • 1998

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