Differential sprouting responses in axonal fiber systems in the dentate gyrus following lesions of the perforant path in WLDs mutant mice.

@article{Shi1996DifferentialSR,
  title={Differential sprouting responses in axonal fiber systems in the dentate gyrus following lesions of the perforant path in WLDs mutant mice.},
  author={Bertram Shi and Brent B. Stanfield},
  journal={Brain research},
  year={1996},
  volume={740 1-2},
  pages={89-101}
}
Axons in both peripheral nerves and central fiber pathways undergo very slow Wallerian degeneration in Wlds mutant mice. It has recently been shown that in Wlds mutant mice there is a delay in the intensification of acetylcholinesterase histochemical staining in the molecular layer of the dentate gyrus following lesions of the entorhinal cortex. Thus, it appears that delayed post-lesion reactive sprouting is associated with the delayed degeneration of cut central axons in this mutant. We have… CONTINUE READING