Differential signalling during B-cell maturation.

  title={Differential signalling during B-cell maturation.},
  author={Margaret M Harnett and Elad Katz and Catriona A. Ford},
  journal={Immunology letters},
  volume={98 1},
The molecular mechanism by which the antigen receptors (BCR) on B cells can elicit differential maturation state-specific responses is one of the central problems in B-cell differentiation yet to be resolved. Indeed, many of the early signalling events detected following BCR ligation, such as activation of protein tyrosine kinases (PTK), phospholipase C… CONTINUE READING