Differential sensitivity of head and neck cancers to non-major histocompatibility-restricted killer cell activity.

@article{Schantz1990DifferentialSO,
  title={Differential sensitivity of head and neck cancers to non-major histocompatibility-restricted killer cell activity.},
  author={Stimson Pryor Schantz and Tamas Racz and Nelson G. Ord{\'o}{\~n}ez and Nicholas H. A. Terry and D. Lans ing Taylor and Samuel P. Bugis and Peter G. Sacks},
  journal={The Journal of surgical research},
  year={1990},
  volume={48 2},
  pages={154-64}
}
Cell lines derived from squamous cell carcinoma of the upper aerodigestive tract (head and neck cancer) were phenotypically characterized with regard to differential sensitivity to nonmajor histocompatibility restricted (non-MHCr) killer cell activity. Requirements for detectable lysis of the cell lines in a standard chromium release assay included either isolation of fresh enriched Leu 19+ large granular lymphocytes (both Leu 19+CD3+ and Leu 19+CD3- populations) or interleukin-2 (IL-2… CONTINUE READING