Differential sensitivity of cerebellar purkinje neurons to ethanol in selectively outbred lines of mice: maintenance in vitro independent of synaptic transmission.


The effects of ethanol on spontaneous firing of cerebellar Purkinje neurons were examined in outbred lines of mice (short-sleep, SS; and long-sleep, LS) which exhibit differential behavioral sensitivity to ethanol. In order to determine whether the differences in Purkinje cell ethanol sensitivity which are observed in situ reflect differences in intrinsic… (More)


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