Differential sensitivities to hyperbaric oxygen of lymphocyte subpopulations of normal and autoimmune mice.

@article{Xu1997DifferentialST,
  title={Differential sensitivities to hyperbaric oxygen of lymphocyte subpopulations of normal and autoimmune mice.},
  author={X Xu and Hong Yi and Masaki Kato and Hiroshi Suzuki and Shinichiro Kobayashi and Hidemi Takahashi and Izumi Nakashima},
  journal={Immunology letters},
  year={1997},
  volume={59 2},
  pages={79-84}
}
We studied the effect of exposure to hyperbaric oxygen (HBO): 2.8 atm absolute 100% oxygen for 4 h daily over 3-7 days, on the immune system of normal (BALB/c and MRL- +/+) and autoimmune MRL-lpr/lpr) mice. In HBO exposed BALB/c mice, we observed a remarkable decrease in the cell population of the spleen and thymus. We found that the sensitivity to HBO varied among subpopulations of lymphocytes. For example, CD4+ CD8+ double positive cells in the thymus and B220+ B cells in the spleen were more… CONTINUE READING