Differential roles of dorsal hippocampal subregions in spatial working memory with short versus intermediate delay.

@article{Lee2003DifferentialRO,
  title={Differential roles of dorsal hippocampal subregions in spatial working memory with short versus intermediate delay.},
  author={Inah Lee and Raymond P. Kesner},
  journal={Behavioral neuroscience},
  year={2003},
  volume={117 5},
  pages={1044-53}
}
In order to determine the role of subregions of the hippocampus in spatial working memory, this study combined selective neurotoxic lesions of the hippocampal subregions with a simple delayed nonmatching-to-place task on a radial maze in rats. Lesions of the dentate gyrus or the CA3, but not the CA1, subregion of the hippocampus induced a deficit in the acquisition of the task with short-term delays (i.e., 10 sec) and impaired performance of the task in a novel environment. All subregional… CONTINUE READING

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