Differential roles of NR2A and NR2B-containing NMDA receptors in LTP and LTD in the CA1 region of two-week old rat hippocampus.

@article{Bartlett2007DifferentialRO,
  title={Differential roles of NR2A and NR2B-containing NMDA receptors in LTP and LTD in the CA1 region of two-week old rat hippocampus.},
  author={Thomas E. Bartlett and Neil J Bannister and Valerie J. Collett and Sheila L. Dargan and Peter Vernon Massey and Zuner Assis Bortolotto and Stephen M Fitzjohn and Zafar Iqbal Bashir and Graham L Collingridge and David Lodge},
  journal={Neuropharmacology},
  year={2007},
  volume={52 1},
  pages={60-70}
}
The role of NMDA receptors in the induction of long-term potentiation (LTP) and long-term depression (LTD) is well established but which particular NR2 subunits are involved in these plasticity processes is still a matter of controversy. We have studied the effects of subtype selective NMDA receptor antagonists on LTP induced by high frequency stimulation… CONTINUE READING