Differential roles of HIC-5 isoforms in the regulation of cell death and myotube formation during myogenesis.

@article{Gao2007DifferentialRO,
  title={Differential roles of HIC-5 isoforms in the regulation of cell death and myotube formation during myogenesis.},
  author={Zheng-Liang Gao and Ryan Deblis and H Fredrickson Glenn and Lawrence M. Schwartz},
  journal={Experimental cell research},
  year={2007},
  volume={313 19},
  pages={
          4000-14
        }
}
Hic-5 is a LIM-Only member of the paxillin superfamily of focal adhesion proteins. It has been shown to regulate a range of biological processes including: senescence, tumorigenesis, steroid hormone action, integrin signaling, differentiation, and apoptosis. To better understand the roles of Hic-5 during development, we initiated a detailed analysis of Hic-5 expression and function in C(2)C(12) myoblasts, a well-established model for myogenesis. We have found that: (1) myoblasts express at… CONTINUE READING
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