Differential roles for NOD2 in osteoblast inflammatory immune responses to bacterial pathogens of bone tissue.

@article{Chauhan2010DifferentialRF,
  title={Differential roles for NOD2 in osteoblast inflammatory immune responses to bacterial pathogens of bone tissue.},
  author={Vinita S. Chauhan and Ian Marriott},
  journal={Journal of medical microbiology},
  year={2010},
  volume={59 Pt 7},
  pages={
          755-62
        }
}
Osteoblasts produce an array of immune molecules following bacterial challenge that can contribute to inflammation and the recruitment of leukocytes to sites of infection during bone diseases such as osteomyelitis. However, the mechanisms by which osteoblasts perceive and respond to facultative intracellular pathogens such as Salmonella species and Staphylococcus aureus have not been determined. Recently, our laboratory has described the expression in osteoblasts of members of the nucleotide… CONTINUE READING

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