Differential responsiveness of normal and simian virus 40-transformed human fibroblast cells to interferon-gamma.

@article{Karasaki1992DifferentialRO,
  title={Differential responsiveness of normal and simian virus 40-transformed human fibroblast cells to interferon-gamma.},
  author={Yuji Karasaki and Takuji Katoh and Katsumi Higashi and Sadao Gotoh},
  journal={Journal of interferon research},
  year={1992},
  volume={12 3},
  pages={185-90}
}
The effect of interferon-gamma (IFN-gamma) on epidermal growth factor (EGF) receptor binding and the proliferation of normal and simian virus 40 (SV40)-transformed human fibroblast cells was compared under identical culture conditions. IFN-gamma induced an enhancement of EGF binding to normal cells, whereas it decreased the EGF binding to SV40-transformed… CONTINUE READING