Differential responses to natural and recombinant allergens in a murine model of fish allergy.

@article{Ventel2011DifferentialRT,
  title={Differential responses to natural and recombinant allergens in a murine model of fish allergy.},
  author={Michelle L van der Ventel and Natalie Eva Nieuwenhuizen and Frank Kirstein and Christoph Hikuam and Mohamed F Jeebhay and I Swoboda and Frank Brombacher and Andreas Ludwig Lopata},
  journal={Molecular immunology},
  year={2011},
  volume={48 4},
  pages={637-46}
}
Aerosolized fish proteins are an important cause of allergic airway reactions in both the domestic and the occupational environment. The aim of this study was to investigate inhalant fish-induced allergy in a mouse model and compare immune responses generated by raw and heat-treated fish extracts as well as natural and recombinant forms of the major fish allergen parvalbumin. Mice were sensitized with raw or cooked pilchard extract and challenged intranasally with cooked pilchard extract… CONTINUE READING
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