Differential responses of osteoblasts and macrophages upon Staphylococcus aureus infection

  title={Differential responses of osteoblasts and macrophages upon Staphylococcus aureus infection},
  author={Therwa Hamza and Bingyun Li},
  booktitle={BMC Microbiology},
Staphylococcus aureus (S. aureus) is one of the primary causes of bone infections which are often chronic and difficult to eradicate. Bacteria like S. aureus may survive upon internalization in cells and may be responsible for chronic and recurrent infections. In this study, we compared the responses of a phagocytic cell (i.e. macrophage) to a non-phagocytic cell (i.e. osteoblast) upon S. aureus internalization. We found that upon internalization, S. aureus could survive for up to 5 and 7 days… CONTINUE READING

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