Differential responses of human neural and hematopoietic stem cells to ethanol exposure.

@article{Hao2003DifferentialRO,
  title={Differential responses of human neural and hematopoietic stem cells to ethanol exposure.},
  author={Hsiao-Nan Hao and Graham C. Parker and Jane Zhao and Kaveh Barami and William D. Lyman},
  journal={Journal of hematotherapy & stem cell research},
  year={2003},
  volume={12 4},
  pages={
          389-99
        }
}
The mechanisms underlying fetal developmental defects caused by maternal ethanol (EtOH) consumption remain unclear. The symptoms of fetal alcohol syndrome (FAS) include neurological and immunological dysfunctions that are linked to cell reduction in these systems. Neural (NSC) and hematopoietic stem cells (HSC) may be targets for the cytotoxic effects of EtOH. Furthermore, protein kinase C (PKC) signal transduction systems of these stem cells may be involved in EtOH-induced cell death. Purified… CONTINUE READING

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