Differential response to neoadjuvant chemotherapy among 7 triple-negative breast cancer molecular subtypes.

@article{Masuda2013DifferentialRT,
  title={Differential response to neoadjuvant chemotherapy among 7 triple-negative breast cancer molecular subtypes.},
  author={Hiroko Masuda and Keith A. Baggerly and Ying Wang and Ya Zhang and Ana Mar{\'i}a Gonz{\'a}lez-Angulo and Funda Meric-Bernstam and Vicente Valero and Brian D. Lehmann and Jennifer A. Pietenpol and Gabriel N Hortobagyi and W. Fraser Symmans and Naoto T Ueno},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2013},
  volume={19 19},
  pages={5533-40}
}
PURPOSE The clinical relevancy of the 7-subtype classification of triple-negative breast cancer (TNBC) reported by Lehmann and colleagues is unknown. We investigated the clinical relevancy of TNBC heterogeneity by determining pathologic complete response (pCR) rates after neoadjuvant chemotherapy, based on TNBC subtypes. EXPERIMENTAL DESIGN We revalidated the Lehmann and colleagues experiments using Affymetrix CEL files from public datasets. We applied these methods to 146 patients with TNBC… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 61 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 165 extracted citations

Pathological Response in a Triple-Negative Breast Cancer Cohort Treated with Neoadjuvant Carboplatin and Docetaxel According to Lehmann's Refined Classification.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2018
View 4 Excerpts
Highly Influenced

Downregulation of TBC1 Domain Family Member 24 (BC1D24) Inhibits Breast Carcinoma Growth via IGF1R/PI3K/AKT Pathway

Medical science monitor : international medical journal of experimental and clinical research • 2018

References

Publications referenced by this paper.
Showing 1-10 of 24 references

Genomic index of sensitivity to endocrine therapy for breast cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2010

Supervised risk predictor of breast cancer based on intrinsic subtypes.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2009
View 1 Excerpt

Similar Papers

Loading similar papers…