Differential response of Porphyromonas gingivalis to varying levels and duration of hydrogen peroxide-induced oxidative stress.

@article{McKenzie2012DifferentialRO,
  title={Differential response of Porphyromonas gingivalis to varying levels and duration of hydrogen peroxide-induced oxidative stress.},
  author={Rachelle M E McKenzie and Neal A Johnson and Wilson Aruni and Yuetan Dou and Godfred L. Masinde and H M Fletcher},
  journal={Microbiology},
  year={2012},
  volume={158 Pt 10},
  pages={
          2465-79
        }
}
Porphyromonas gingivalis, an anaerobic oral pathogen implicated in adult periodontitis, can exist in an environment of oxidative stress. To evaluate its adaptation to this environment, we have assessed the response of P. gingivalis W83 to varying levels and durations of hydrogen peroxide (H(2)O(2))-induced stress. When P. gingivalis was initially exposed to a subinhibitory concentration of H(2)O(2) (0.1 mM), an adaptive response to higher concentrations could be induced. Transcriptome analysis… CONTINUE READING

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