Differential rescue of visceral and cardiac defects in Drosophila by vertebrate tinman-related genes.

@article{Park1998DifferentialRO,
  title={Differential rescue of visceral and cardiac defects in Drosophila by vertebrate tinman-related genes.},
  author={Moonsoo Park and Choy Lewis and D Turbay and A D Chung and Jennifer N Chen and Sylvia Evans and Roger E. Breitbart and Mark C Fishman and Seigo Izumo and Rolf Bodmer},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1998},
  volume={95 16},
  pages={9366-71}
}
tinman, a mesodermal NK2-type homeobox gene, is absolutely required for the subdivision of the early Drosophila mesoderm and for the formation of the heart as well as the visceral muscle primordia. Several vertebrate relatives of tinman, many of which are predominately expressed in the very early cardiac progenitors (and pharyngeal endoderm), also seem to promote heart development. Here, we show that most of these vertebrate tinman-related genes can readily substitute for Drosophila tinman… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

References

Publications referenced by this paper.

Park et al

  • G. Ranganayakulu, D. A. Elliott, R. P. Harvey, Olson, E. N. Development, in press. Developmental Biology
  • Proc. Natl. Acad. Sci. USA 95
  • 1998

Similar Papers

Loading similar papers…