Differential requirement for NF-kappa B family members in control of helminth infection and intestinal inflammation.

@article{Artis2002DifferentialRF,
  title={Differential requirement for NF-kappa B family members in control of helminth infection and intestinal inflammation.},
  author={David Artis and Sagi Shapira and Nicola Mason and Kendra M. Speirs and Michael Goldschmidt and J. Carlos Caama{\~n}o and Hsiou-chi Liou and Christopher A Hunter and Phillip Scott},
  journal={Journal of immunology},
  year={2002},
  volume={169 8},
  pages={4481-7}
}
The NF-kappaB family of transcription factors is critical in controlling the expression of a wide range of immune response genes. However, whether individual family members perform specific roles in regulating immunity and inflammation remains unclear. Here we investigated the requirement for NF-kappaB1, NF-kappaB2, and c-Rel in the expression of Th2 cytokine responses, development of host protective immunity, and regulation of intestinal inflammation following infection with the gut-dwelling… CONTINUE READING