Differential regulation of zinc transporter 1, 2, and 4 mRNA expression by dietary zinc in rats.

@article{Liuzzi2001DifferentialRO,
  title={Differential regulation of zinc transporter 1, 2, and 4 mRNA expression by dietary zinc in rats.},
  author={Juan P Liuzzi and Raymond K. Blanchard and Robert J. Cousins},
  journal={The Journal of nutrition},
  year={2001},
  volume={131 1},
  pages={
          46-52
        }
}
Zinc metabolism is well regulated over a wide range of dietary intakes to help maintain cellular zinc-dependent functions. Expression of transporter molecules, which influence zinc influx and efflux across the plasma and intracellular membranes, contributes to this regulation. We have examined in rats the comparative response of zinc transporters 1, 2, and 4 (ZnT-1, ZnT-2 and ZnT-4) to dietary zinc. ZnT-1 and ZnT-4 are expressed ubiquitously, whereas ZnT-2 is limited to small intestine, kidney… CONTINUE READING

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