Differential regulation of sympathetic neuron neuropeptide Y and catecholamine content and secretion.

@article{May1995DifferentialRO,
  title={Differential regulation of sympathetic neuron neuropeptide Y and catecholamine content and secretion.},
  author={Victor May and Christiane Brandenburg and Karen M. Braas},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1995},
  volume={15 6},
  pages={4580-91}
}
Cultured principal neurons of the superior cervical ganglion (SCG), which coexpress high levels of catecholamines and neuropeptide Y (NPY), were used as a model to simultaneously examine whether sympathetic neuronal peptide and transmitter content or secretion are differentially regulated. Accumulation of NPY immunoreactivity and the dopamine metabolites DOPAC and HVA in SCG neuronal conditioned culture medium was used as an index of NPY and catecholamine secretion, respectively. Release of NPY… CONTINUE READING